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US President Donald Trump has confirmed that the US has launched "major combat operations" in Iran. His comments came after Israeli Defence Minister Israel Katz said his country had launched a "pre-emptive" attack on the country. The BBC's Jon Donnison said military action was something that had been anticipated "for weeks". Follow live update on

A series of bilateral health agreements being negotiated between African countries and the administration of President Donald Trump have been labelled “clearly lop-sided” and “immoral” amid growing outrage at US demands, including countries being forced to share biological resources and data. It emerged this week that Zimbabwe had halted negotiations with the US for $350m

The Green Party's Hannah Spencer has won the Gorton and Denton by-election, with 14,980 votes. She beat Reform UK’s Matt Goodwin with 10,578 votes, and Labour’s Angeliki Stogia with 9,364 votes. The constituency had long been considered a safe Labour seat, with the vote triggered by the resignation of former Labour MP Andrew Gwynne in

A drone attack by a paramilitary group has hit a vehicle carrying displaced families in central Sudan, killing at least 24 people, including eight children, a doctors’ group said on Saturday. The attack by the Rapid Support Forces took place close to the city of Er Rahad in North Kordofan province, according to the Sudan

Iain Watson Political correspondent Getty Images A pay-off given to Lord Mandelson after he was sacked as ambassador to the US is being reviewed, UK Foreign Office sources have told the BBC. The review was instigated after fresh details emerged about the peer's contact with Jeffrey Epstein and a separate police investigation was initiated in

The Iberian peninsula has been placed under severe weather alerts as Storm Leonardo continues to batter parts of Spain and Portugal with torrential rain and strong winds. Since Tuesday, the slow-moving system has brought widespread disruption, flooding and evacuations. In Grazalema, in southern Spain, more than 700mm of rain has fallen since Wednesday, roughly equivalent

Richard Wheeler Political reporter Getty Images Officers arrived at one of the addresses linked to Lord Mandelson in central London Two properties linked to Peter Mandelson in Wiltshire and north London have been searched following allegations of misconduct in public office, the Metropolitan Police has said. The force launched an investigation into the ex-Labour minister

The traditional chief of a village in western Nigeria where jihadists massacred residents earlier this week has recounted a night of terror during which the attackers killed two of his sons and kidnapped his wife and three daughters. Umar Bio Salihu, the 53-year-old chief of Woro, a small, Muslim-majority village in Kwara state, said that

Hugo Bachega Middle East correspondent AFP via Getty Images The US negotiators will be led by special envoy Steve Witkoff (left), while the Iranian team is headed by Foreign Minister Abbas Araghchi Senior US and Iranian officials are expected to meet in Oman later for direct talks amid a crisis that has raised fears of

More than 160 people have been killed in two villages in western Nigeria in the country’s deadliest armed assaults this year, as communities reel from repeated and widespread acts of violence perpetrated by jihadists and other armed groups. The death toll from Tuesday’s attacks in Woro and Nuku in Kwara state stood at 162 on